Yorkie drives Ras-induced tumor progression by microRNA-mediated inhibition of cellular senescence

Although activating mutations in the GTPase Ras promote cancer, Ras also induces cellular senescence, a barrier that is necessary to overcome for Ras activation to promote tumor progression. Using a model of Ras-induced tumor growth in flies, Ito and Igaki found that Ras-induced cellular senescence required the ETS family transcription factor Pnt. Loss of cell […]

Read More »

How stem cells synchronize to repair the spinal cord in axolotls

The spinal cord is an important component of our central nervous system: it connects the brain with the rest of the body and plays a crucial part in coordinating our sensations with our actions. Falls, violence, disease—various forms of trauma can cause irreversible damage to the spinal cord, leading to paralysis, sometimes even death.

Read More »

Recovering from a Stroke with MSCs Stem Cells

Stroke is an abrupt interruption of constant blood flow to the brain that causes loss of neurological function, there are 3 types:  a blocked artery (ischemic stroke) or leaking or bursting of a blood vessel (hemorrhagic stroke) and transient ischemic attack (TIA also known as a mini stroke ). Different factors can lead to a stroke: high blood pressure, high […]

Read More »